Spravato Treatment

Spravato® (esketamine) is a prescription nasal spray for treatment-resistant depression. It works differently from traditional antidepressants. 

Spravato treatment provides transformative relief from depression symptoms. It is an FDA-approved ketamine therapy accessible to patients.

Spravato Treatment

Spravato® (esketamine) is a prescription nasal spray for treatment-resistant depression. It works differently from traditional antidepressants.
Spravato treatment provides transformative relief from depression symptoms. It is an FDA-approved ketamine therapy accessible to patients.

Spravato Treatment for Depression

Depression does not look the same for everyone, and for many people, standard antidepressants simply do not provide enough relief. That is where Spravato treatment comes in. At The Health Experiences, our esketamine clinic offers Spravato as a clinically supervised, FDA-approved option for people who have tried other treatments without success.
What makes Spravato treatment stand out is how quickly it can take effect. Many patients begin to notice a shift in their symptoms within hours of their first session, something most traditional antidepressants cannot deliver. This is because the Spravato® works on the brain’s glutamate system, potentially leading to rapid and sustained improvements in mood.
Doctor discussing with patient in medical office.
Therapist and patient in a counseling session.
Doctor discussing with patient in medical office.

Spravato Treatment for Depression

Depression does not look the same for everyone, and for many people, standard antidepressants simply do not provide enough relief. That is where Spravato treatment comes in. At The Health Experiences, our esketamine clinic offers Spravato as a clinically supervised, FDA-approved option for people who have tried other treatments without success.

What makes Spravato treatment stand out is how quickly it can take effect. Many patients begin to notice a shift in their symptoms within hours of their first session, something most traditional antidepressants cannot deliver. This is because the Spravato® works on the brain’s glutamate system, potentially leading to rapid and sustained improvements in mood.

Administered as a nasal spray in a monitored clinical setting, Spravato treatment is non-invasive and designed around patient comfort and safety.

If you or someone you care about has been stuck in a cycle of treatment after treatment with little to no improvement, our esketamine clinic is here to offer a medically sound and compassionate alternative.

Meet Our Experienced Care Team in Cincinnat

Our providers are skilled, compassionate, and dedicated to your integrated care. Led by Medical Director Dr. Emmett Cooper, our team includes psychiatric nurse practitioners, therapists, and primary care professionals committed to providing the highest quality behavioral health and medical care in the Cincinnati area.
Conditions that Spravato treatment may help include:

Treatment-Resistant Depression (TRD)

Major Depressive Disorder (MDD)

Major Depressive Disorder with Suicidal Ideation (MDSI)

Drug Use Disorder

Drug Addiction

Chronic Depression

Anxiety Co-occurring with Depression

Our providers are skilled, compassionate, and dedicated to your integrated care. Led by Medical Director Dr. Emmett Cooper, our team includes psychiatric nurse practitioners, therapists, and primary care professionals committed to providing the highest quality behavioral health and medical care in the Cincinnati area.

What Makes Spravato Treatment Effective

Most conventional antidepressants work by increasing levels of chemicals like serotonin, norepinephrine, and dopamine in the brain. These chemicals carry messages between brain cells, and the idea is that having more of them improves communication and lifts mood over time.
Spravato treatment takes a different path. Esketamine increases levels of glutamate, the most abundant chemical messenger in the brain. Because glutamate plays such a wide role in brain function, targeting it means Spravato can influence a much larger number of brain cells simultaneously. The result is a faster, broader impact on mood and mental health compared to traditional options.
At our esketamine clinic, this distinction matters because it means patients who have not responded to other antidepressants still have a real, effective option available to them, one backed by clinical research and FDA approval.
Healthcare professional and patient discussing with clipboard.
Doctor discussing with elderly woman using tablet.

Your Spravato Treatment Experience at Our Esketamine Clinic

Knowing what to expect makes the process feel far less overwhelming. Here is your journey at The Health Experiences esketamine clinic.
It begins with a thorough evaluation. Our clinical team reviews your full mental health history, previous treatments, and current medications to confirm that Spravato treatment is the right path for you. Once approved, your sessions are scheduled in our clinic under direct medical supervision.
During each session, you self-administer the nasal spray under the guidance of our clinical staff. You then remain in the clinic for approximately 2 hours while our team monitors your response. Some patients experience mild dizziness or a temporary feeling of detachment during this phase, both of which are expected and pass before you leave.
Sessions are typically scheduled according to your condition and then reduced over time as your symptoms improve. Most patients begin noticing meaningful changes within the first few weeks. At our esketamine clinic, your comfort, safety, and progress are our priority from the very first session to the last.

Your Spravato Treatment Experience at Our Esketamine Clinic

Knowing what to expect before starting any new treatment makes the process feel far less overwhelming.

Here is a clear picture of what your Spravato treatment journey looks like at The Health Experiences esketamine clinic.

It begins with a thorough evaluation. Our clinical team reviews your full mental health history, previous treatments, and current medications to confirm that Spravato treatment is the right path for you. Once approved, your sessions are scheduled in our clinic under direct medical supervision.

During each session, you self-administer the nasal spray under the guidance of our clinical staff. You then remain in the clinic for approximately 2 hours while our team monitors your response. Some patients experience mild dizziness or a temporary feeling of detachment during this phase, both of which are expected and pass before you leave.

Sessions are typically scheduled according to your condition and then reduced over time as your symptoms improve. Most patients begin noticing meaningful changes within the first few weeks. At our esketamine clinic, your comfort, safety, and progress are our priority from the very first session to the last.

Your Spravato Treatment Experience

Knowing what to expect makes the process feel far less overwhelming. Here is your journey at The Health Experiences esketamine clinic.

01

Thorough Evaluation

It begins with a thorough evaluation. Our clinical team reviews your full mental health history, previous treatments, and current medications to confirm that Spravato treatment is the right path for you. Once approved, your sessions are scheduled in our clinic under direct medical supervision.

02

The Treatment Session

During each session, you self-administer the nasal spray under the guidance of our clinical staff. You then remain in the clinic for approximately 2 hours while our team monitors your response. Some patients experience mild dizziness or a temporary feeling of detachment, which are expected and pass before you leave.

03

Progress & Recovery

Sessions are typically scheduled according to your condition and then reduced over time as your symptoms improve. Most patients begin noticing meaningful changes within the first few weeks. Your comfort, safety, and progress are our priority from the first session to the last.

Conditions Our Esketamine Clinic Addresses

Spravato treatment is designed for patients dealing with serious, persistent mental health conditions, particularly those who have not found relief through standard care. At our esketamine clinic, we work with each patient to determine whether Spravato is the right fit for their specific diagnosis and treatment history.

Conditions that Spravato treatment may help include:

  • Treatment-Resistant Depression (TRD)
  • Major Depressive Disorder (MDD)
  • Major Depressive Disorder with Suicidal Ideation (MDSI)
  • Drug Use Disorder
  • Drug Addiction
  • Chronic Depression
  • Anxiety Co-occurring with Depression

It is worth noting that while Spravato treatment is not a standalone cure, it works most effectively alongside other forms of care, such as therapy and medication management.

Some psychiatrists have also observed that patients dealing with drug use disorder and addiction, particularly where depression plays a contributing role, show improvements in managing cravings and resisting substance use when Spravato treatment is part of their overall plan.

Our esketamine clinic takes a whole-person approach, ensuring Spravato is used as part of a broader, well-rounded treatment strategy.

Conditions Our Esketamine Clinic Addresses

Spravato treatment is designed for patients dealing with serious, persistent mental health conditions, particularly those who have not found relief through standard care. At our esketamine clinic, we work with each patient to determine whether Spravato is the right fit for their specific diagnosis and treatment history.

Conditions that Spravato treatment may help include:

  • Treatment-Resistant Depression (TRD)
  • Major Depressive Disorder (MDD)
  • Major Depressive Disorder with Suicidal Ideation (MDSI)
  • Drug Use Disorder
  • Drug Addiction
  • Chronic Depression
  • Anxiety Co-occurring with Depression

It is worth noting that while Spravato treatment is not a standalone cure, it works most effectively alongside other forms of care, such as therapy and medication management. Some psychiatrists have also observed that patients dealing with drug use disorder and addiction, particularly where depression plays a contributing role, show improvements in managing cravings and resisting substance use when Spravato treatment is part of their overall plan.

Our esketamine clinic takes a whole-person approach, ensuring Spravato is used as part of a broader, well-rounded treatment strategy.

Healthcare professional and patient discussing with clipboard.

What Makes Spravato Treatment Effective

Most conventional antidepressants work by increasing levels of chemicals like serotonin, norepinephrine, and dopamine in the brain. These chemicals carry messages between brain cells, and the idea is that having more of them improves communication and lifts mood over time.

Spravato treatment takes a different path. Esketamine increases levels of glutamate, the most abundant chemical messenger in the brain. Because glutamate plays such a wide role in brain function, targeting it means Spravato can influence a much larger number of brain cells simultaneously. The result is a faster, broader impact on mood and mental health compared to traditional options.

At our esketamine clinic, this distinction matters because it means patients who have not responded to other antidepressants still have a real, effective option available to them, one backed by clinical research and FDA approval.

Your Spravato Treatment Experience at Our Esketamine Clinic

Knowing what to expect before starting any new treatment makes the process feel far less overwhelming.

Here is a clear picture of what your Spravato treatment journey looks like at The Health Experiences esketamine clinic.

It begins with a thorough evaluation. Our clinical team reviews your full mental health history, previous treatments, and current medications to confirm that Spravato treatment is the right path for you. Once approved, your sessions are scheduled in our clinic under direct medical supervision.

During each session, you self-administer the nasal spray under the guidance of our clinical staff. You then remain in the clinic for approximately 2 hours while our team monitors your response. Some patients experience mild dizziness or a temporary feeling of detachment during this phase, both of which are expected and pass before you leave.

Sessions are typically scheduled according to your condition and then reduced over time as your symptoms improve. Most patients begin noticing meaningful changes within the first few weeks. At our esketamine clinic, your comfort, safety, and progress are our priority from the very first session to the last.